Research at IBMP
Our research extends to the fields of bioanalytics, clinical pharmacy, clinical pharmacology, TDM, etc. To get an insight into our work, we recommend searching in specialist literature: PubMed, search for "Sörgel F"
Google: search for e.g.
Sörgel F
Sörgel F antibiotics
Sörgel pharmacokinetics
Sörgel Ehrlich
Sörgel Würzburg
Sörgel acrylamide
Sörgel F cocaine
Sörgel F doping
CV of the head of the institute
Prof. Dr. Fritz Sörgel, head of the institute
IBMP-Institut für Biomedizinische und Pharmazeutische Forschung e.V.
Paul-Ehrlich-Straße 19
90562 Nürnberg-Heroldsberg
Tel. +49 911 518 290
Fax: +49 911 518 29 28
e-Mail: ibmp@osn.de
Studies
1971-1976
Study of pharmacy at the Johann-Wolfgang-Goethe University, Frankfurt/ Main; Graduation with state examination
1980-1986
Study of scientific part of medicine (Physics and clinical subjects) at the Friedrich-Alexander-University, Erlangen
Doctorate
December 21, 1978
Scientific doctorate to Dr. phil. nat.* at the Johann-Wolfgang-Goethe University, Frankfurt/ Main:
"Experimental studies on the biochemical and pharmacological characterization of salidiuretics in humans and animals."
*The Johann-Wolfgang-Goethe University, Frankfurt/ Main does not award the title “Dr. rer. nat.”, but “Dr. phil. nat."
Habilitation
January 29, 1987
"Pharmacokinetic basis of antibiotic therapy for cystic fibrosis"
Appointed private lecturer at the University of Essen
Appointed extraordinary professor June 24, 1994, Medical Faculty of the University of Essen
Scientific work
1976-1979
HOECHST AG Frankfurt/ Main, Department of Clinical Pharmacology "First in human“ studies
1979-1980
School of Pharmacy at the Medical Center of the University of California, San Francisco, USA as a scholarship holder of the German Research Foundation (DFG)
1980-1984
Department of Toxicology at the Institute of Forensic Medicine at the University of Erlangen-Nürnberg and Head of the Department of Clinical Pharmacology at the CKI Institute for Cardiovascular Diseases, Erlangen
1984-1986
University Clinic for pediatrics of the University of Essen
Since 1987
Head of the Institute for Biomedical and Pharmaceutical Research e.V., Paul-Ehrlich-Str. 19, 90562 Nürnberg-Heroldsberg
Academic teachers
Prof. Dr. Dr. E. Mutschler, Prof. Dr., K. Thoma, Prof. Dr., H. Oelschläger, Prof. Dr. G. Schneider, all Frankfurt/ Main
Prof. Dr. L. Z. Benet, Prof. Dr. S. Riegelman, both San Francisco, USA
Prof. Dr. Dr. M. Geldmacher-von Mallinckrodt, Prof. Dr. H. Kersten, Prof. Dr. W. Kersten, Prof. Dr. H. zur Hausen (Nobel Prize in Medicine, 2008), all Erlangen
Prof. Dr. U. Stephan, Essen
Publications
A total of about 250 original publications, thereof 203 (Sörgel F) in MEDLINE - listed journals, three of which are under Soergel F. (as of April 30, 2020)
70 supplements,
50 book contributions,
800 congress abstracts,
400 lectures
Teaching activities
Since January 1987
as a faculty member and adjunct professor at the Institute for Pharmacology of the Medical Faculty of the University of Duisburg-Essen
Lectures:
General pharmacology and toxicology I and II: antibiotics, pharmacokinetics, toxicology
Special pharmacology: antibiotic therapy
Since summer semester 1999
Lecturer for "Clinical Pharmacy" at the Bavarian Julius Maximilians University in Würzburg, Faculty of Chemistry and Pharmacy
Subjects:
Clinical studies
Drug side effects
Antibiotic therapy
Bioequivalence
Since winter semester 2007
Regular guest lectures at the Ludwig Maximilians University in Munich, Faculty of Chemistry and Pharmacy: Biotechnological drugs - biosimilars
1995-2002
Lecturer for "Clinical Pharmacy" Rheinische Friedrich-Wilhelms-Universität Bonn, Faculty of Mathematics and Natural Sciences
International scientific work and functions
2006-2008
President of the “International Society of Antiinfective Pharmacology” (ISAP), www.isap.org
2004 and 2008
Congress President 1st/ 2nd World Conference on Magic Bullets (guests from 84 countries) Conference to celebrate Paul Ehrlich's 150th birthday/ 100th Anniversary of Nobel Prize (guests from 100 countries), www.ehrlich2004.org; www.ehrlich-2008.org
Since 2001
Chief editor of the "Chemotherapy" journal listed in Medline
Since 2006
Review Board "Recent Patents on Anti-Infective Drug Discovery"
Since 2009
Editorial Board Member: “Journal of Bioequivalence & Bioavailability”
Since 2012
International Editorial Advisory Board: GaBi (Generics and Biosimilar Initiative) Journal
Work in scientific committees (national)
09/1992-09/2005
Paul Ehrlich Society: Board member and head of various working groups
06/2006-10/2012
Member of the Academy for "Clinical Pharmacy" of the Bavarian Chamber of Pharmacists
Expert for drug approval authorities
No further information possible due to the necessary confidentiality
Scientific awards
07/1990
International Prize for "Innovative Studies on Quinolones" during the 3rd Quinolone Meeting in Vancouver, Canada
2015
Foundation of Professor Dr. Dr. Schunack Prize in memory of the co-founder of the Free University of Berlin
Non-scientific awards
12/10/2007
Cross of Merit on ribbon of the Order of Merit of the Federal Republic of Germany by Federal President Prof. Dr. H. Koehler
Research priorities
Scientifically worked with a total of approx. 200 different pharmaceutical substances, including:
All substances used in oncology, e.g. tyrosine kinase inhibitors
Development of a special program to optimize drug therapy for oncological patients (PEAK)
Therapeutic proteins and biosimilars
Erythropoietin (EPO), interferons, pegylated interferons, G-CSF
Growth hormone
ELISA - Methods for Therapeutic Proteins
Anti-infectives, incl. their use in seriously ill and cystic fibrosis patients
Asthma substances: steroids and Beta 2 mimetics
Metabolism of calcium and fluorides
Cardiovascular substances
Anti-inflammatory drugs, pharmacokinetics and local tolerance
Studies with generics (approx. 300studies)
Contamination of drugs with nitrosamines
Investigations of homeopathic drugs
Focus in the laboratory
LC-MS/ MS (90% of the work)
Immunological techniques (ELISA)
Flow cytometry
Methodical work
Physiological pharmacokinetics
Fabric mirror
Structure-kinetics relationships
Penetration of antibiotics in CNS (central nervous system)
Penetration of antibiotics in bones
Cytochrome P450
Pharmacokinetics/ pharmacodynamics relationships
Examples: urinary tract infections, respiratory infections, bone infections
Pharmacogenetics
Bio-terrorism
NIH - funded project at the University of New York in Albany and the IBMP, Nürnberg-Heroldsberg (the only European institute involved in this project)
New detection methods for cocaine
to estimate consumption
SCIENCE Vol 316, April 6, 2007, “Hard Data on Hard Drugs, Grabbed From the Environment”. The science magazine SCIENCE reports on the work at the IBMP.
Inclusion of our data in the UN report June 2007: Estimation of cocaine use through innovative methods at the IBMP
Work with molecules and substances of "public interest"
Doping, state institutions:
Expert of the public prosecutor's office in Tübingen in the "Baumann toothpaste affair"
Doping substance analysis for the public prosecutor's office in Munich I
(Main public prosecutor's office: doping and drug offenses, or violations of the drug law)
Sole lecturer for the field of pharmacology (one of three days) at the judges academy in Trier, the cadre forge for prosecutors in the field of doping and drug crime, or violations of the drug law
Member of the anti-doping commission for the evaluation of the University Clinic Freiburg with Prof. Letizia Paoli (Leuven) and Prof. Franke (Heidelberg), 2015-2016
Invitation to the presentation in the sports committee of the German Bundestag on the subject of “UV radiation of blood” in Erfurt
Doping, sports associations:
Member of the Anti-Doping Commission of the Federation of German Cyclists (BDR)
Lecturer at the German Swimming Association (DSV)
Doping, media:
Media consultant in the GHG scandal, EPO in the "Armstron case"
Epo-doping: numerous interviews and guest contributions in SZ, FAZ, Tagesspiegel, DER SPIEGEL, FOCUS, ARD, ZDF, Arte, Nürnberger Nachrichten, etc.
Pechstein case: Page 2- Contribution in the SZ- "Außenansicht": "Pechstein disease"
arte documentation "Doping until the heart fails" (2019)
Other topics and areas of activity
- Wastewater analysis to determine drug and drug consumption
- Expert "Neosino scandal" about dietary supplements
- Acrylamide metabolism in humans (breast milk, placenta transfer)
- e cigarette
- Worldwide horror: TV report on antibiotic production in India as a joint project with NDR, WDR and SZ, in collaboration with Prof. Lübbert, Leipzig University Hospital (2017)
- ZDF/ arte "Globules and Good Faith - Homeopathy under Test" (2018)
- Clarification of impurities with the blood pressure medicine valsartan (2018)
- ARD: "Business with the globules" (2020)
Non-scientific activities
Paul Ehrlich historian
Author of a play about Paul Ehrlich ("I wished I lived today"), as well as the musical “Magic Bullets" about Paul Ehrlich. Both were premiered on September 10, 2004 in the Fürth town hall on the occasion of the world congress on the 150th birthday of Paul Ehrlich in front of 1200 visitors from 84 countries. The German version of the play about Paul Ehrlich was published on September 2, 2006 at the Paul Ehrlich Institute in Frankfurt ("Georg-Speyer-Haus") premiered on the occasion of the 100th anniversary of the institute. A special version to mark the 90th anniversary of Paul Ehrlich's death was premiered on August 20, 2005 in Bad Homburg (where Paul Ehrlich died).
October 4, 2008: Performance of a new version during EHRLICH II.
Several articles in Journals about Paul Ehrlich not listed in Medline
Planning a Paul Ehrlich museum
Estimated number of previous visitors to Paul Ehrlich exhibitions in Europe and North America: 10,000
Planned permanent exhibitions in the museum: Gerhard Domagk, Richard Willstätter, Jacob Henle, Alois Alzheimer, Albert Hofmann
Thematic exhibitions: Medicalization of society with a focus on the history of pharmaceuticals from the mid-19th century, dietary supplements, functional food, doping, drugs
In the Nürnberg Museum of Industry since 2007 (Exhibition area on 'speed'): Small exhibition of doping substances and methods put together
To support the most important German museum, the institute’s museum loans exhibits to them. So far, around 200,000 have seen the exhibits in Berlin and Frankfurt/ Main.
In honor of Paul Ehrlich
2004/2008
Scientists from 84 countries, or 100 countries respectively, meet at the world congresses organized by the IBMP in Nürnberg on antibiotics and cancer treatments.
2015
Ceremonial lecture by the head of the institute at the celebration of the 100th anniversary of the death of Paul Ehrlich at Goethe University Frankfurt/ Main.
Nürnberg Paul Ehrlich Days in the historic town hall on the 100th anniversary of the Nobel Prize winner's death.
2018
Annual meeting with the 2009 Nobel Laureate in Chemistry, Prof. Dr. Ada Yonath, Jerusalem, at the Paul Ehrlich award ceremony in the Paulskirche. The award winner discovered the mechanisms of action of antibiotics, which the IBMP is also intensively researching.
Support of partner high schools to promote the natural sciences
1997-2005
Scheinfeld High School (Mittelfranken, in the Steigerwald). Four winners of the regional “Jugend forscht” competition, third place at the federal level
2007-2010
Gymnasium Eckental and Gymnasium Lauf
2009
Award for the TOP-TEN of the best cooperations in Germany by the Robert Bosch Foundation "School meets science"
Press release from the Robert Bosch Foundation
The “School meets Science” award is an award for the joint work of teachers and scientists who are committed to finding new ways to get students excited about science and technology with great commitment and innovative ideas. It was under the patronage of Professor Dr. Annette Schavan, Member of the Bundestag, retired Federal Minister of Education and Research.
